40 Top Healthcare Startups to Watch in 2022

Two women working in a lab.

Healthcare companies today face an uphill battle. Even as healthcare costs skyrocket, health outcomes continue to decline. As a result, healthcare startups largely aim to improve patient care, with the bigger goal of changing the face of treatments today.

Within the healthcare sector, a wide range of services and products are available. Some of the top healthcare startups are using artificial intelligence (AI) to help predict the efficacy of certain treatments, while others help older people discover the right Medicare plan for them. No matter where the industry is heading, digital innovation and technology will be a key cornerstone.

Recommended: Learn how to launch your own company by reading our comprehensive guide on how to start a startup.

Best Healthcare Startups to Follow

Every year, new startups pull to the forefront of their industry through exciting innovation and industry-disrupting business models. We’ve created a list of top healthcare startups that startup-lovers, investors, and aspiring entrepreneurs should follow in 2022.

Disclaimer: With so many exciting healthtech startups launching and growing worldwide, we aren’t able to cover them all. Furthermore, the startups that are listed below are not officially ranked and are listed in no particular order.

1. Headspace

  • Location: Santa Monica, California
  • Founders: Andy Puddicombe, Richard Pierson
  • Founded In: 2010
  • Funding: Secondary Market, $215.9 Million
  • Investors Include: Bull and Bear, Empede Capital, Times Bridge

Headspace is an accessible digital health platform and app known primarily for its meditation and mindfulness exercises. This platform boasts hundreds of hours of content for users and a free introduction to the basics of meditation. App users also have access to a variety of videos and chat options to optimize their mental health and wellbeing.

Check out more digital health startups to watch.

2. Circles

  • Location: San Francisco, California
  • Founders: Dan Landa, Irad Eichler
  • Founded In: 2020
  • Funding: Series A, $24.5 Million
  • Investors Include: NFX, Ronald Cohen, Lior Ron

Circles is a mental healthcare startup that is revolutionizing the way consumers access support groups. Through the company’s laser-focused, professionally-led groupings and accessible pricing, users are able to more easily access the care and support they need.

Check out our interview with the founder of Circles!

3. Modern Fertility

  • Location: San Francisco, California
  • Founders: Afton Vechery, Carly Leahy, Tom Chokel
  • Founded In: 2017
  • Funding: Series A, $22 Million
  • Investors Include: Forerunner Ventures, Sound Ventures, Steph Korey

Modern Fertility is changing the way women have access to fertility hormones by creating a simple at-home test. Women can consult with a doctor to determine if a test is necessary and then take a fertility test in the comfort of their own home. Results pop up in the app on any phone device, giving women reliable healthcare at affordable prices.

4. Paige

  • Location: New York, New York
  • Founders: David Klimstra, Norman Selby, Peter Schüffler, Thomas Fuchs
  • Founded In: 2018
  • Funding: Series C, $220 Million
  • Investors Include: Casdin Capital, Catalio Capital Management, Healthcare Venture Partners

Paige was created specifically for pathologists, introducing artificial intelligence (AI) to healthcare professionals so they can make more informed treatment decisions. This diagnostic platform is intuitive and designed to minimize costs without compromising a patient’s safety or privacy. It’s the first company in its sector to receive the breakthrough designation from the FDA.

See more AI startups to follow.

5. Levels

  • Location: New York, New York
  • Founders: Andrew Conner, Casey Means, David Flinner, Josh Clemente, Sam Corcos
  • Founded In: 2019
  • Funding: Series A, $50 Million
  • Investors Include: Generation Ventures, Ben Gilbert, AirAngels

Levels is a health and wellness startup that offers a platform for monitoring metabolic fitness through real-time blood glucose tracking. The goal of the platform is to provide users with an effective tool to optimize their own health through diet and exercise.

Discover more fitness startups.

6. Parsley Health

  • Location: New York, New York
  • Founders: Joel Wishkovsky, Robin Berzin
  • Founded In: 2016
  • Funding: Series B, $36 Million
  • Investors Include: Sand Hill Angels, H Venture Partners, Gaingels

Parsley Health is an innovative take on modern healthcare and primary care. By offering a platform that integrates cutting-edge medical testing and technology as well as impactful nutrition, wellness, and prevention research, Parsley Health provides customers with a holistic medicine experience.

Discover more top startups in NYC.

7. Bloom Diagnostics

  • Location: Zurich, Switzerland
  • Founders: Angelica Kohlmann, MD Ph.D.p, Thomas Kohlmann Kupper
  • Founded In: 2018
  • Funding: Series B, $21 Million
  • Investors Include: Speedinvest, Walter Ventures, Thomas Pfisterer

Bloom Diagnostics provides a democratized medical test experience, putting consumers' health back in their own hands. Users of Bloom Diagnostics’ products are able to track, maintain, and improve their health using the startups’ diagnostic devices.

8. Trusted Health

  • Location: San Francisco, California
  • Founders: Lennie Sliwinski, Matt Pierce, Sarah Gray
  • Founded In: 2017
  • Funding: Series C, $174.5 Million
  • Investors Include: Greenspring Associates, Craft Ventures, Felicis Ventures

Trusted Health is a digital platform for nurses to utilize in order to find and obtain flexible work opportunities. Users are able to create resumes and share credentials to apply for opportunities all on one platform.

9. SonderMind

  • Location: Denver, Colorado
  • Founders: Mark Frank, Sean Boyd
  • Founded In: 2014
  • Funding: Series C, $183 Million
  • Investors Include: Quiet Capital, F-Prime Ventures, Smash Ventures

SonderMind is a telehealth startup that is taking on the behavioral health industry to create a more accessible and effective patient experience. With their integrated provider network, software tools, and data-powered analytics, SonderMind provides valuable insights into health systems and connects patients with therapists inside their insurance network.

Discover more top startups in Denver.

10. Wellframe

  • Location: Boston, Massachuesettes
  • Founders: Anne Bosilevac, Archit Bhise, Chase Zaputil, Jacob Sattelmair, Melissa Herman, Sandhya Gardner, Trishan Panch, Vinayak Ramesh
  • Founded In: 2011
    Funding: Series C, $45.2 Million
  • Investors Include: Threshold, F-Prime Capital, BlueCross BlueShield Ventures Partners

Wellframe is a creative startup aimed at changing the process of onboarding to a health care plan. They aim to provide the necessary resources to make people feel confident and supported by their healthcare plans. The company increases the number of customer touchpoints and even sets up reminders and checklists.

See more top Boston startups.

11. HealthSherpa

  • Location: San Francisco, California
  • Founders: Catherine Perez, George Kalogeropoulos, Michael Wasser, Ning Liang
  • Founded In: 2013
  • Funding: Series N/A, $6.6 Million
  • Investors Include: The Valley Fund, Core Innovation Capital

Next up on our list of top healthcare startups is HealthSherpa. Health coverage is more important now than ever before, and HealthSherpa provides users with everything they need to apply for, obtain, and utilize health insurance. This startup is a Heathcare.gov certified web broker that provides services to a litany of communities.

12. Opencare

  • Location: San Francisco, California
  • Founders: Alex Chyrtsik, Cameron Howieson, Nikolai Bratkovski
  • Founded In: 2012
  • Funding: Series A, $24.6 Million
  • Investors Include: 8VC, Heron Rock Fund, Jonathan Swanson

Opencare is a healthcare startup that aims to provide the best dental care to patients by developing the first premium dental care network. Users can find high-quality dentists through the platform, and top dentists can use the platform to grow their practices and find new patients.

13. Alan

  • Location: Paris, France
  • Founders: Charles Gorintin, Jean Charles Samuelian
  • Founded In: 2016
  • Funding: Series E, $558.2 Million
  • Investors Include: Ribbit Capital, Coatue, Teachers’ Venture Growth

Alan is an innovative digital health insurance startup that prioritizes patient needs by focusing on price and quality. The goal of this startup is to create a better insurance industry by revolutionizing the health insurance industry to meet the needs of individuals and companies while building consumer trust.

Feeling inspired? Learn how to launch your company with our guide on how to start a startup.

14. PatientPop

  • Location: Santa Monica, California
  • Founders: Luke Kervin, Travis Schneider
  • Founded In: 2014
  • Funding: Series C, $125 Million
  • Investors Include: Toba Capital, Vivo Capital, HLM Venture Partners

PatientPop is a growth platform for healthcare providers that helps them to harness the power of technology to streamline processes and provide superior patient care. The platform automates each step of the patient’s journey, from booking to follow-up appointments, making the healthcare experience positive for the patient and provider.

15. Meru Health

  • Location: San Mateo, California
  • Founders: Albert Nazander, Kristian Ranta, Riku Lindholm
  • Founded In: 2016
  • Funding: Grant, $53.3 Million
  • Investors Include: National Institute of Mental Health, JP Morgan, FMZ Ventures

Meru Health combines modern technology with scientific data to create a comprehensive app with treatment plans for people with mental illnesses. They source professional therapists and psychiatrists with behavioral and mindful practices to create mental health solutions. They offer a 12-week program and conduct the entire course through their app.

Discover more of the top Silicon Valley startups.

16. Vori Health

  • Location: San Francisco, California
  • Founders: Mary O'Connor, Ryan Grant
  • Founded In: 2020
  • Funding: Series A, $50 Million
  • Investors Include: Alley Corp, Echo Health Ventures, Max Ventures

Vori Health is a healthcare startup that uses a holistic approach to healthcare, prioritizing musculoskeletal care. Their services are all-inclusive, providing physical medicine and therapy, rehabilitation care, prescriptions, imaging and labs, health coaching, and more. All of their services are provided by a network of board-certified physicians.

17. NexHealth

  • Location: San Francisco, California
  • Founders: Alamin Uddin, Waleed Asif
  • Founded In: 2014
  • Funding: Series C, $177.2 Million
  • Investors Include: Scott Belsky, Shahed Khan, Packy McCormick

NexHealth is an OS designed for patients. The open data layer in Electronic Health Records (EHRs) is the information that connects developers, doctors, and patients to everything from messaging to payments to bookings. The standardized API provided by NexHealth makes it possible for everyone involved to stay more informed about a patient’s health while managing their treatment, billing, and follow-up plans.

18. IntelyCare

  • Location: Quincy, Massachusetts
  • Founders: Chris Caulfield, David Coppins, Ike Nnah, Prince Nnah
  • Founded In: 2014
  • Funding: Series C, $170.8 Million
  • Investors Include: Kaiser Permanente Ventures, Longitude Capital, Janus Henderson Investors

Next on our list of top healthcare startups is IntelyCare. With more flexibility for nursing professionals than ever before, IntelyCare makes it possible for nurses to schedule their shifts on their own terms. From pay to hours, the software posts all of the relevant details for each job, allowing nurses to create their own lifestyle based on how much money they want to make, how many hours they want to work, etc. The app also makes it possible for healthcare facilities to get the support they need according to the demand in the area.

19. Cityblock Health

  • Location: Brooklyn, New York
  • Founders: Bay Gross, Iyah Romm, Mat Balez, Toyin Ajayi
  • Founded In: 2017
  • Funding: Secondary Market, $891.3 Million
  • Investors Include: Empede Capital, SoftBank, Tiger Global Management

Cityblock Health is a way for people to address gaps in their healthcare coverage. Too many people have basic plans that don’t cover a variety of services, and patients find out too late that they need to pay for the expenses out of pocket. This service works with patient providers to address gaps and then splits the cost savings with the healthcare provider. The idea is that healthier people cost less overall than sick people, and proper coverage will ensure proper preventative care for more people.

20. Somatus

  • Location: McLean, Virginia
  • Founders: Anthony Welters, Ikenna Okezie
  • Founded In: 2016
  • Funding: Series E, $465.1 Million
  • Investors Include: Longitude Capital, Flare Capital Partners, Elevance Health

Somatus is changing the way the industry approaches kidney care. The company is an integrative solution for healthcare providers that treat patients with kidney disease or those who are at risk of kidney disease. The company provides a number of services, including a diagnostic renal team and dialysis provisioning strategies, to ensure that patients and providers can effectively manage kidney health.

21. Hinge Health

  • Location: San Francisco, California
  • Founders: Daniel Perez, Gabriel Mecklenburg
  • Founded In: 2015
  • Funding: Series E, $1 Billion
  • Investors Include: Alkeon Capital, Coatue, Whale Rock Capital Management

Hinge Health is an app that creates physical therapy plans based on people’s needs and lifestyles. This isn’t your standard physical therapy program, like those designed for people who have sustained serious injuries, but an everyday routine that office workers and manual laborers alike can use to increase flexibility and mobility. The exercises can stave off chronic pain, prevent injuries, and improve quality of life at the same time.

22. Oura Ring

  • Location: Oulu, Finland
  • Founders: Kari Kivela, Markku Koskela, Petteri Lahtela
  • Founded In: 2013
  • Funding: Venture, $148.3 Million
  • Investors Include: MSD Capital, Forerunner Ventures, Lifeline Ventures

Oura Ring is a sleep tracker that answers the question of how you really slept the night before. It analyzes REM, light sleep, nightly heart rate, schedule, and deep sleep. Because good health is so tied to the quality of your sleep, the ring can reveal larger patterns about what kind of rest and recuperation you’re really getting at the end of a tough day.

23. Collective Health

  • Location: San Mateo, California
  • Founders: Ali Diab, Rajaie Batniji
  • Founded In: 2013
  • Funding: Series F, $719 Million
  • Investors Include: G Squared, DFJ Growth, PFM Health Sciences

Collective Health helps employers design curated solutions for the workforce. The software is designed to not only challenge the standard benefits of today but to address the changing needs for employees and ensure more beneficial outcomes. The data, insights, and administrative tools give employers more control over their costs, so they’re spending money where it counts.

24. NervGen Pharma

  • Location: Vancouver, Canada
  • Founders: Brian McAlister, Harold Martin Punnett, William Joseph Radvak
  • Founded In: 2017
  • Funding: Post-IPO Equity, $32.6 Million
  • Investors Include: PFP Sciences, CSBio

NervGen Pharma is developing treatments to help the nervous system heal itself. These disorders, which can include anything from spinal injury to Alzheimer’s disease, are the result of damage to the nerves. This bioscience company is currently in Phase 1 of a clinical trial to assess patient response and results.

25. Flatiron Health

  • Location: New York, New York
  • Founders: Nat Turner, Zach Weinberg
  • Founded In: 2012
  • Funding: Series D, $324.9 Million
  • Investors Include: Stripes, Allen & Company, Roche

Flatiron Health is a place where clinicians, researchers, and providers can turn to for answers about how cancer develops, how and why it spreads, and what can be done for patients to ensure they get the best possible care. Cancer is a malicious disease that can ‘trick’ the body, but Flatiron has the resources to level the playing field for providers and ensure patient treatments stay one step ahead.

26. Medable

  • Location: Palo Alto, California
  • Founders: James Sas, Michelle Longmire, Perry Robinson, Tim Smith
  • Founded In: 2015
  • Funding: Series D, $506.6 Million
  • Investors Include: Blackstone Accelerates Growth, Western Technology Investment, Sapphire Ventures

Medable streamlines clinical trials, making the process smoother for patients, clinicians, analyzers, etc. The platform was built from the ground up with the help of patient advocates, technology experts, and clinicians, and it allows healthcare professionals to run decentralized trials in a single system. The company offers a number of products, and customers can customize their experience by selecting only what they need.

27. K Health

  • Location: New York, New York
  • Founders: Adam Singolda, Allon Bloch, Israel Roth, Ran Shaul
  • Founded In: 2016
  • Funding: Series E, $271.3 Million
  • Investors Include: Kaiser Permanente, BoxGroup, Counterpart Advisors, et al.

K Health is a way for people to treat themselves as opposed to their condition — even without insurance. The doctor visits are $35 each, and it’s a $29 monthly membership fee to join. The service offers customers 24/7 via a virtual chat room, so people can get emergency advice without making an appointment or visiting an expensive emergency room.

28. Carbon Health

  • Location: San Francisco, California
  • Founders: Caesar Djavaherian, Eren Bali, Greg Burrell, Pablo Stanley, Tom Berry
  • Founded In: 2015
  • Funding: Secondary Market, $522.5 Million
  • Investors Include: Sand Hill Angels, Nolan Arenado, Ion Pacific

Carbon Health allows patients to manage their health from one place. This includes getting prescription drugs delivered to their doors, accessing medical charts, and scheduling a same-day appointment. The technology is user-friendly and built for patients from all backgrounds, so they can get the information, services, and care they need without delay.

29. Arise

  • Location: New York, New York
  • Founders: Amanda D'Ambra, Joan Zhang
  • Founded In: 2022
  • Funding: Private, $4 Million
  • Investors Include: BBG Ventures, Iyah Romm, Sylvia Romm

Arise is designed to help people with eating disorders. The platform offers virtual support at a time when more than 30 million Americans will experience some type of disorder in their lifetime, and up to 90% of them will never get care for it. The technology supports mental health through community and ongoing aid.

30. Spring Health

  • Location: New York, New York
  • Founders: Abhishek Chandra, Adam Chekroud, April Koh
  • Founded In: 2016
  • Funding: Series C, $295.5 Million
  • Investors Include: RRE Ventures, Able Partners, Kinnevik

Spring Health was created to take the guesswork out of mental health care. Too often, the field is a game of trial-and-error, and every time a treatment option fails (which is 70% of the time), it can bring on new feelings of hopelessness and failure for the patient. This platform is to give people a tailored experience from the very beginning, one that helps them push through barriers faster.

31. Virta Health

  • Location: San Francisco, California
  • Founders: Sami Inkinen
  • Founded In: 2014
  • Funding: Series E, $373 Million
  • Investors Include: Tiger Global Management, Creandum, Tim Kendall

Virta Health was created for people with Type 2 diabetes. It helps patients lower blood sugar and lose weight without having to take medication for their disorder (including insulin). The company shows people that their condition can be reversed quickly and helps them find ways to change their lifestyle to achieve this goal.

32. Runway

  • Location: Miami, Florida
  • Founders: Joshua Rome
  • Founded In: 2021
  • Funding: Undisclosed
  • Investors Include: Undisclosed

Runway helps travelers get the medications they need to ensure their vacations go as smoothly as possible. Because illness is common when people travel, the company is hoping to close the gap between the desire to move around the world and any hesitation that might stand in the way. The company pairs people with a provider, so they have support before and during their trip.

Check out our full list of fast-growing Miami startups.

33. Komodo Health

  • Location: San Francisco, California
  • Founders: Arif Nathoo, Web Sun
  • Founded In: 2014
  • Funding: Series E, $314 Million
  • Investors Include: Tiger Global Management, SVB Capital, Casdin Capital

Komodo Health amalgamates data from patient encounters and powers a massive healthcare map designed to reveal the state of the healthcare system. The innovative algorithms are augmented with decades of clinical experience, and the result is more insights into how health is progressing (or, in some cases, regressing) in America. These trends provide a meaningful look at how doctors can help patients on a path back to better health.

34. Intellect

  • Location: Singapore
  • Founders: Anurag Chutani, Theodoric Chew
  • Founded In: 2019
  • Funding: Series A, $32.8 Million
  • Investors Include: HOF Capital, Singtel Innov8, K3 Ventures

Intellect is paving the way for better mental health for workers in Asia. With so many people suffering from burnout and low productivity, the technology puts people in touch with behavioral coaches and licensed psychologists to improve mental wellbeing. There are also self-guided experiences that people can take on the platform as a means to manage their conditions or gain more insight into their state of mind.

35. Modern Health

  • Location: San Francisco, California
  • Founders: Alyson Watson, Erica Johnson
  • Founded In: 2017
  • Funding: Series D, $167.4 Million
  • Investors Include: Battery Ventures, Founders Fund, Kleiner Perkins

Modern Health is a platform for families who want expert mental health care services without the wait. This is customized care that focuses on everything from pandemic fatigue to racial trauma, and the experiences within the app have led to more people engaging with their mental health. Excellent for both adults and kids, Modern Health is redefining what mental health looks like today and how it should be managed.

36. Tempus

  • Location: Chicago, Illinois
  • Founders: Eric Lefkofsky
  • Founded In: 2015
  • Funding: Debt Financing, $1.1 Billion
  • Investors Include: T. Rowe Price, Franklin Templeton Investments, Baillie Giffords

Tempus is using artificial intelligence (AI) to accelerate, predict, identify, and diagnose different diseases and disorders. The technology helps doctors discover novel targets, find life-saving trials, and identify diseases earlier than ever before. The data can even make it easier for doctors to give better odds to patients before they start treatment.

Discover more top startups in Chicago.

37. Devoted Health

  • Location: Boston, Massachusetts
  • Founders: ​​Edward Park, Jeremy Delinsky, Todd Park
  • Founded In: 2017
  • Funding: Series D, $2 Billion
  • Investors Include: GIC, General Catalyst, Jaws Ventures

Devoted Health is a healthcare startup that helps people choose a Medicare plan. With so many options available (including those that can be augmented with a supplemental plan), it can be confusing for anyone to figure out what the right option is for them. This service helps people dissect the details, so they can choose coverage that will protect them from excessive bills.

38. Medallion

  • Location: San Francisco, California
  • Founders: Derek Lo
  • Founded In: 2020
  • Funding: Series C, $85 Million
  • Investors Include: BoxGroup, GV, Optum Ventures

Medallion is a service that streamlines the credentialing and licensing process for clinical operators. Considering the shortage of healthcare providers, it’s more important than ever for managers to have a service that’s as trustworthy as it is efficient. With smart notifications and automated checks, it’s faster and simpler to meet hiring quotas without compromising patient care.

39. Patina

  • Location: Philadelphia, Pennsylvania
  • Founders: Jack Stoddard
  • Founded In: 2020
  • Funding: Series A, $57 Million
  • Investors Include: GV, F-Prime Capital, Rock Springs Capital

Patina is reimagining primary care for adults aged 65 and up. The goal is to help people build trusted relationships as they manage the aging process by providing a team to help people navigate the system. Experts answer questions, connect patients with specialists, handle administrative tasks, and help people find community resources that can give them a new lease on their mental and physical health.

40. Verge Genomics

  • Location: San Francisco, California
  • Founders: Alice Zhang, Jason Chen
  • Founded In: 2015
  • Funding: Series B, $134.1 Million
  • Investors Include: Eli Lilly, Lifeforce Capital, Vulcan Capital

Verge Genomics is pioneering a drug discovery platform that allows for new drugs to be produced at scale. By using the most advanced artificial intelligence in the industry, the company is poised to solve some of the most challenging issues in healthcare today. The company is looking to develop drugs faster by relying on insights and patterns gleaned from technology.

Recommended: Check out our full list of the top startups to watch in 2022!

FAQs

What is a healthcare startup?

Healthcare startups today are largely using emerging technologies, such as artificial intelligence (AI), the blockchain, and integrated data tools, to advance services and health in the industry. These are innovative solutions that will ultimately improve patient outcomes.

What is a health tech startup?

A health tech startup responds to everyday challenges by integrating new technology into everyday healthcare services. The programs and platforms are there to streamline the process for patients and providers alike. For instance, a health tech startup might use artificial intelligence to predict whether chemo will work for a cancer patient.

What does the future of the healthcare industry look like?

The future of healthcare will depend on how much information can be collected and how we can use that data to give patients more effective, holistic treatment plans. New apps and technologies invite individuals to take charge of their destiny with customized advice and recommendations, which can ultimately improve overall mental and physical well-being.

How do you start a healthcare startup?

Healthcare startups should first seek to solve a glaring gap in the healthcare industry today. With declining patient outcomes all over the nation, there are plenty of ways for a company to step in and address the gaps. You’ll also need a way to monetize your company, such as a subscription service, to ensure that you can recoup your costs (or the costs of any investors who choose to back you).

What are some helpful resources for healthcare startups?

Healthcare startups can look to accelerators, incubators, and VC firms to get the funding they need. Looking through the investors on this list can tell you more about which firms are likely to invest in a healthcare startup.


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