8 Top Philadelphia Startups to Watch in 2024

Philadelphia cityscape.

Philadelphia is home to more than great sandwiches and a winning football team. Their startup scene is burgeoning with innovations across several sectors, boasting startups making waves in global markets. 

Many of their top startups hail from the biotechnology and healthcare sectors, providing solutions for diagnostics and patient data. However, there are also many early-stage and growth-stage startups in a variety of different industries calling Philadelphia home. These are the top Philadelphia startups to watch this year.

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Best Startups in Philadelphia to Follow

Every year, new startups pull to the forefront of their industry through exciting innovation and industry-disrupting business models. We’ve rounded up the most exciting Philadelphia startups of 2024 that startup lovers, investors, and aspiring entrepreneurs should follow. 

Disclaimer: With so many exciting Philly startups launching and growing, we aren’t able to cover them all. Furthermore, the startups listed below are not officially ranked and are listed in no particular order.

1. iEcure

  • Industry: Biotech 
  • Founders: Jim Wilson
  • Founded In: 2012 
  • Funding: $115 Million 
  • Investors Include: Novo Holdings, Versant Ventures 

iEcure is a biotechnology, specifically in vivo gene-editing, startup that is on a mission to cure “loss of function” diseases with devastating effects. The startup boasts a partnership with the GTP as well as over 300 experts in various fields supporting their mission. 

2. GoPuff

  • Industry: Ecommerce, Apps, Food & Beverage
  • Founders: Rafael Ilishayev, Yakir Gola
  • Founded In: 2013
  • Funding: $3.4 Billion 
  • Investors Include: Robert Iger, BroadLight Capital 

GoPuff is a wildly successful product delivery company founded in 2013. The service provides digital delivery services, getting customers products within minutes of ordering, from groceries to home goods. 

3. HealthVerity

  • Industry: Healthcare, Information Technology (IT) 
  • Founders: Andrew Goldberg, Andrew Kress
  • Founded In: 2014
  • Funding: $142.2 Million 
  • Investors Include: Greycroft, Foresite Capital 

HealthVerity is a healthcare startup leveraging healthcare and consumer data to propel science forward with compliance and security at the forefront of its services. With HealthVerity, any stakeholders in the medical system, from patients to doctors, can integrate data to provide a more comprehensive patient data set. 

4. NeuroFlow

  • Industry: Wellness, Healthtech 
  • Founders: Adam Pardes, Christopher Molaro 
  • Founded In: 2017
  • Funding: $57.8 Million 
  • Investors Include: SEMCAP, Concord Health Partners, Mission Daybreak

NeuroFlow optimizes behavioral and mental health care through a HIPAA-compliant health platform. Their cloud-based digital platform offers healthcare professionals a robust tool for tracking, monitoring, and improving patient care from psychology to primary care. 

5. Burro

  • Industry: Agtech, Artificial Intelligence (AI)
  • Founders: Charles Andersen, Deniz Ilhan, Terry Scott, Vibhor Sood
  • Founded In: 2017
  • Funding: $12.7 Million 
  • Investors Include: Radicle Growth, ff Venture Capital 

Burro is an AI-driven agtech solution. Their autonomous platform helps farms and other outdoor areas through robotic autonomous supply and cargo delivery, eliminating much of the physical strain required for roles in these environments. 

6. Proscia

  • Industry: AI, Biotech 
  • Founders: Coleman Stavish, David West, Nathan Buchbinder
  • Founded In: 2014
  • Funding: $70.6 Million 
  • Investors Include: Robin Hood Ventures, Razor’s Edge Ventures 

Proscia combines software, artificial intelligence, and biology to advance research and diagnostics for diseases like cancer. Their AI-powered platform, Concentriq®, allows diagnostic labs and pharmaceutical companies to use data to drive results and find much-needed cures. 

7. Guru

  • Industry: SaaS, AI, Software 
  • Founders: Mitchell Stewart, Mitchell Stewart, Rick Nucci
  • Founded In: 2013
  • Funding: $70.7 Million 
  • Investors Include: Accel, Emergence 

Guru is an AI-powered knowledge management system combining enterprise search, intranet, and wiki all in one. With integrations with some of the top software used by businesses, including Slack, Gusto, and Microsoft Teams, Guru is on a mission to boost productivity, streamline workflows, and increase team knowledge. 

8. dbt Labs

  • Industry: Big Data, Analytics, IT 
  • Founders: Connor McArthur, Drew Banin, Tristan Handy
  • Founded In: 2016
  • Funding: $414.4 Million
  • Investors Include: Andreessen Horowitz, Sequoia, Amplify Partners

Formerly Fishtown Analytics, dbt Labs is an analytics startup streamlining the work of data analysts through creation and dissemination optimizations. With more than 30,000 companies using the platform, dbt Labs has become a major player in data development tools. 

Recommended: Check out our full list of the top startups to watch!