38 Top Digital Health Startups to Watch Out for in 2022

Person having a telehealth call with a medical professional.

Since 2020, a large percentage of the population has utilized telemedicine services to see their doctor, therapist, or other healthcare providers.

Since the COVID-19 pandemic took the world by storm, healthcare providers have had to adapt and take patient appointments online through remote tools and technology solutions. Fortunately, several digital health startups have flourished within the last several years, developing innovative solutions that have transformed the healthcare industry.

With the demand for virtual healthcare alternatives on the rise, digital health companies have received a well-deserved spotlight. These are the top digital health startups of 2022.

Recommended: Learn how to launch your own company by reading our comprehensive guide on how to start a startup.

Top Digital Health Companies

Maintaining your health and well-being is crucial to quality of life, and these companies have developed innovative, virtual solutions for healthcare needs, from hassle-free dentistry to accessible mental health care. Meet the top digital health startups that are revolutionizing telemedicine.

Disclaimer: With so many exciting digital health companies launching and growing worldwide, we aren’t able to cover them all. Furthermore, the startups that are listed below are not officially ranked and are listed in no particular order.

1. Cerebral

  • Location: San Francisco, California
  • Founders: Ho Anh, Kyle Robertson
  • Founded In: 2020
  • Funding: $462 Million
  • Investors Include: Access Industries, SoftBank Vision Fund

Cerebral is a digital mental healthcare startup that makes accessing professionals in this field easier than ever by providing a virtual alternative to traditional appointments. Additionally, Cerebral offers medication management services, ensuring patients are never without necessary pharmaceuticals.

2. Dascena

  • Location: Oakland, California
  • Founders: Ritankar Das
  • Founded In: 2014
  • Funding: $50 Million
  • Investors Include: Frazier Healthcare Partners

Dascena takes the future of medicine literally with digital services that leverage the capabilities of machine learning for early disease prevention and optimized patient care.

3. PatientPop

  • Location: Santa Monica, California
  • Founders: Luke Kervin, Travis Schneider
  • Founded In: 2014
  • Funding: $125 Million
  • Investors Include: HLM Venture Partners, Leerink Transformation Partners, Toba Capital

Founded in 2014, PatientPop provides technologies designed to help healthcare providers grow their practice and attract more patients in addition to automating a variety of processes for patients and providers alike. With PatientPop, physicians are able to create an optimized web presence that will make it easier for potential patients to discover their services as well as create automated email marketing campaigns.

4. Cohere Health

  • Location: Boston, Massachusetts
  • Founders: Duncan Reece, Siva Namasivayam
  • Founded In: 2019
  • Funding: $56.1 Million
  • Investors Include: Polaris Partners, Define Ventures, Flare Capital Partners

The connection between patient, provider, and healthcare plan is the primary focus of Cohere Health. This digital SaaS and healthcare company aims to create improved, effective healthcare journeys for patients by increasing the quality of care and transparency across the entire patient care journey.

Discover more of the top Boston startups to watch.

5. Kindbody

  • Location: New York, New York
  • Founders: Gina Bartasi, Joanne Schneider
  • Founded In: 2018
  • Funding: $125.3 Million
  • Investors Include: Claritas Health Ventures

Kindbody is next up on our list of top digital health startups. This company is revolutionizing the fertility, gynecology, and family-planning sector of the healthcare industry by combining technology and healthcare to offer a range of services, including embryo freezing and in-vitro fertilization.

Discover more top startups in NYC.

6. Carbon Health

  • Location: San Francisco, California
  • Founders: Caesar Djavaherian, Eren Bali, Greg Burrell, Pablo Stanley, Tom Berry
  • Founded In: 2015
  • Funding: $522.5 Million
  • Investors Include: Ion Pacific, Intersect Capital, Lux Capital, Dragoneer Investment Group

Carbon Health is putting healthcare back into the hands of patients by providing an improved virtual healthcare experience, including access to virtual primary care appointments and its own coronavirus assessment tool.

7. Vault Health

  • Location: New York, New York
  • Founders: Jason Feldman
  • Founded In: 2018
  • Funding: $30 Million
  • Investors Include: Tiger Global Management

Vault Health offers men’s medicine virtually through their digital platform that provides everything from specialty care to occupational health services for men without the hassle of in-person visits.

Feeling inspired? Learn how to launch your company with our guide on how to start a startup.

8. Learn to Live

  • Location: Minneapolis, Minnesota
  • Founders: Dale Cook, Russell Morfitt
  • Founded In: 2012
  • Funding: $15.3 Million
  • Investors Include: Blue Cross and Blue Shield of Minnesota

One of the biggest reasons why we are currently dealing with a mental health crisis in our country is the fact that mental health services are simply not as readily accessible as other healthcare services. Learn to Live, though, is a company attempting to solve this pressing issue via an online platform that allows people to connect with therapists in a digital environment. Learn to Live offers customizable online programs for people dealing with stress, anxiety, and depression based on the principles of Cognitive Behavioral Therapy (CBT).

9. H1

  • Location: New York, New York
  • Founders: Ariel Katz, Ian Sax
  • Founded In: 2017
  • Funding: $70.9 Million
  • Investors Include: Goldman Sachs, Transformation Capital, Menlo Ventures

H1 is a healthcare platform that brings the power of digital health to life sciences companies, hospitals, and more to connect a variety of healthcare professionals and allow users to locate impactful clinical research.

10. Modern Health

  • Location: San Francisco, California
  • Founders: Alyson Watson, Erica Johnson
  • Founded In: 2017
  • Funding: $167.4 Million
  • Investors Include: Founders Fund, Battery Ventures

Modern Health’s innovative health app brings together all of the important aspects of maintaining mental well-being all on one platform. From therapy and coaching to self-guided courses, managing mental health is simple and accessible with Modern Health.

We also recommend checking out our full list of the top startups to watch.

11. Medable

  • Location: Palo Alto, California
  • Founders: James Sas, Michelle Longmire, Perry Robinson, Tim Smith
  • Founded In: 2015
  • Funding: $202.6 Million
  • Investors Include: Tiger Global Management, GSR Ventures, Sapphire Ventures, Blackstone Accelerates Growth

Medable is changing how the healthcare industry does clinical research and predictive medicine through its powerful and innovative platform that leverages the power of patient data to generate impactful insights.

Discover more of the top Silicon Valley startups.

12. BrightInsight

  • Location: San Jose, California
  • Founders: Benjamin Lee, Ferry Tamtoro, Kal Patel
  • Founded In: 2017
  • Funding: $166 Million
  • Investors Include: General Catalyst, Insight Partners, Eclipse Ventures

BrightInsight is a digital health IoT platform for medtech and biopharma companies. With BrightInsight, companies can manage and optimize drugs, devices, and medical software by using helpful insights and data.

13. Paige

  • Location: New York, New York
  • Founders: David Klimstra, Norman Selby, Peter Schüffler, Thomas Fuchs
  • Founded In: 2018
  • Funding: $220 Million
  • Investors Include: Casdin Capital, Johnson & Johnson Innovation, Goldman Sachs, Breyer Capital

Digital diagnostics meets the power of artificial intelligence with Paige, a digital healthcare company that empowers patients and care teams to make educated, effective treatment decisions through the development of computational pathology products.

14. Sidecar Health

  • Location: El Segundo, California
  • Founders: Patrick Quigley, Veronica Osetinsky
  • Founded In: 2018
  • Funding: $163 Million
  • Investors Include: Drive Capital, Cathay Innovation

Up next on our list of top digital health companies is Sidecar Health, an insurtech startup that is changing the way patients see health insurance through a personalized approach. Customers are able to quickly and easily create personalized insurance plans that suit their needs and budget with the reassurance of full transparency about medical costs and payouts.

15. Tend

  • Location: New York, New York
  • Founders: Andrew Grover, Doug Hudson, Kathleen Lendvay, Michael Stenclik
  • Founded In: 2019
  • Funding: $198 Million
  • Investors Include: Addition, GV, Redpoint

Being afraid of the dentist may be a thing of the past with Tend, a personalized, stress-free dental service startup that is focused on the patient experience — whether they are in need of a simple check-up or implants and veneers.

16. Twistle

  • Location: Seattle, Washington
  • Founders: Harjinder Sandhu, Jacob Reider, Kulmeet Singh
  • Founded In: 2011
  • Funding: $37.8 Million
  • Investors Include: Providence Ventures, Christiana Care Health Systems, MemorialCare Innovation Fund, Health Enterprise Partners

Twistle is a digital healthcare company that makes it easier than ever for care teams to connect with patients and ensure their treatment is on the right track. From automated follow-ups to secure lab sharing, clinical teams are able to communicate with patients more effectively and securely.

Check out our full list of the top Seattle startups to watch.

17. WorkIt Health

  • Location: Ann Arbor, Michigan
  • Founders: Lisa McLaughlin, Robin McIntosh
  • Founded In: 2015
  • Funding: $138.2 Million
  • Investors Include: Insight Partners, FirstMark

Combating substance abuse has become a vital healthcare objective, and it's an objective that WorkIt Health is committed to furthering. WorkIt Health is a virtual addiction treatment service that allows those who are suffering from substance addiction to recover from home via medication and online therapy. By making addiction recovery services more convenient and accessible, WorkIt Health is playing a prominent role in helping combat substance abuse and addiction.

18. Spring Health

  • Location: New York, New York
  • Founders: Abhishek Chandra, Adam Chekroud, April Koh
  • Founded In: 2016
    Funding: $295.5 Million
  • Investors Include: Kinnevik, Tiger Global Management, Rethink Impact

Spring Health is a mental healthcare startup that provides employers with resources to positively impact their employees’ mental wellness by utilizing the capabilities of artificial intelligence and machine learning.

Discover more startups transforming healthcare with AI.

19. Papa

  • Location: Miami, Florida
  • Founders: Alfredo Vaamonde, Andrew Parker, Jake Rothstein
  • Founded In: 2017
  • Funding: $241.2 Million
  • Investors Include: SoftBank Vision Fund, Tiger Global Management

Papa is an innovative elder-care startup that connects college students with seniors to provide assistance with transportation, home maintenance, and more, as well as much-needed companionship, allowing them to live independently without sacrificing safety and support.

See also our full list of fast-growing Miami startups to watch.

20. Alma

  • Location: New York, New York
  • Founders: Harry Ritter
  • Founded In: 2018
  • Funding: $90.5 Million
  • Investors Include: Insight Partners

Alma provides access to a network of mental health care providers through a membership-based platform that makes accessing mental health services accessible and affordable without sacrificing quality of care.

21. Galileo Health

  • Location: New York, New York
  • Founders: Tom X Lee
  • Founded In: 2018
  • Funding: Unknown
  • Investors Include: Oak HC/FT, 0X Capital, DNA Capital

Galileo Health is focused on bringing health care closer to people’s homes just by using your mobile device. Traditionally, doctors can be hard to reach and even more difficult to spend an extended amount of time with, something that Galileo is changing at its core. Their services provide a dedicated team of doctors and nurse practitioners who are on call 24/7 and ready to deliver full-spectrum medical care.

22. Truepill

  • Location: San Francisco, California
  • Founders: Sid Viswanathan, Umar Afridi
  • Founded In: 2016
  • Funding: $255.4 Million
  • Investors Include: Oak HC/FT, Optum Ventures

Truepill is transforming consumer healthcare by providing a healthcare infrastructure connected through an application programming interface (API) to help healthcare providers improve their patient’s experiences.

23. Virta Health

  • Location: San Francisco, California
  • Founders: Sami Inkinen
  • Founded In: 2014
  • Funding: $373 Million
  • Investors Include: Tiger Global Management, Caffeinated Capital, Sequoia Capital Global Equities

Virta Health provides a clinically proven type 2 diabetes treatment that can reverse its effects, as well as the effects of several other chronic metabolic diseases. Essentially, they provide blood sugar control without the drugs, helping lower patients’ blood sugar levels and help them lose weight.

24. Wellframe

  • Location: Boston, Massachusetts
  • Founders: Anne Bosilevac, Archit Bhise, Chase Zaputil, Jacob Sattelmair, Melissa Herman, Sandhya Gardner, Trishan Panch, Vinayak Ramesh
  • Founded In: 2011
  • Funding: $45.2 Million
  • Investors Include: BlueCross BlueShield Venture Partners, F-Prime Capital, Threshold

Wellframe is an innovative healthcare company that empowers health plans to support patients and make them feel like they’re truly being cared for and supported by their insurance plans. The Wellframe Digital Health Management platform allows health plans to be the best they can be.

25. Lyra Health

  • Location: San Francisco, California
  • Founders: Bob Kocher, David Ebersman, Dena Bravata
  • Founded In: 2015
  • Funding: $910.1 Million
  • Investors Include: Dragoneer Investment Group, Coatue, Addition

Lyra Health is dedicated to helping companies improve mental health care access for their employees. When employees are healthy and an organization maintains a healthy culture, the company and overall business also tend to thrive as a result. Workforce mental health is a significant challenge that Lyra Health is tackling head-on.

26. Commure

  • Location: San Francisco, California
  • Founders: Eugene Kuznetsov, Hemant Taneja
  • Founded In: 2017
  • Funding: $542.3 Million
  • Investors Include: Greenoaks Capital, Human Capital

Commure has developed an operating system (OS) designed specifically for the healthcare industry. It solves healthcare system and dataset fragmentation problems and bridges these systems for critical data, staff, and clinicians to stay connected and in the loop.

27. Verge Genomics

  • Location: San Francisco, California
  • Founders: Alice Zhang, Jason Chen
  • Founded In: 2015
  • Funding: $134.1 Million
  • Investors Include: BlackRock, Eli Lilly

Verge Genomics is using machine learning and human genomics insights to accelerate drug discovery. They are using the power of AI to unlock new drugs at scale in order to solve some of the most significant medical challenges we currently have in our time.

28. Hinge Health

  • Location: San Francisco, California
  • Founders: Daniel Perez, Gabriel Mecklenburg
  • Founded In: 2015
  • Funding: $1 Billion
  • Investors Include: Coatue, Tiger Global Management

Hinge Health is a digital clinic built with the patient in mind that helps treat chronic musculoskeletal conditions. By delivering exercise therapy digitally in a personalized way, Hing Health is able to benefit patients requiring physical therapy, physical therapists and healthcare providers, and the healthcare industry s a whole.

29. Transcarent

  • Location: San Francisco, California
  • Founders: Glen Tullman
  • Founded In: 2020
  • Funding: $298 Million
  • Investors Include: Human Capital, Threshold, Northwell Health

Transcarent is a startup company that’s focused on health and care experiences and is building solutions that make it easy to get affordable, high-quality care for patients. They built a brand new health and care experience that puts the patient in charge and provides transparent information with trusted guidance.

30. BetterUp

  • Location: San Francisco, California
  • Founders: Alexi Robichaux, Eddie Medina
  • Founded In: 2013
  • Funding: $566.9 Million
  • Investors Include: Wellington Management, Lightspeed Venture Partners, ICONIQ Growth

BetterUp Care provides a comprehensive mental health solution to redefine employee productivity and engagement and help businesses grow. People perform best when their mental health is in an optimal state, and BetterUp Care is helping make mental health a priority.

31. Sword Health

  • Location: New York, New York
  • Founders: Márcio Colunas, Virgílio Bento
  • Founded In: 2015
  • Funding: $323.5 Million
  • Investors Include: Sapphire Ventures

Sword Health is on a mission to free 2 billion people on the globe from pain. They are transforming the healthcare sector by providing digital physical therapy solutions, on-call physical health specialists, and access to videos, research, and the tools necessary for patients to experience holistic recovery.

32. Headspace

  • Location: Santa Monica, California
  • Founders: Andy Puddicombe, Richard Pierson
  • Founded In: 2010
  • Funding: Unknown
  • Investors Include: Blisce, Impede Capital

Headspace is a digital health platform that gives users a wide variety of mindfulness training and meditation sessions in order to improve their headspace and mental health. When people meditate consistently, they experience benefits for stress, movement, focus, and sleep.

33. Peppy

  • Location: London, United Kingdom
  • Founders: Evan Harris, Max Landry, Mridula Pore
  • Founded In: 2018
  • Funding: $10.3 Million
  • Investors Include: Felix Capital, Outward VC

Peppy Health is a UK-based startup that has built a digital health app in order to connect people to real human health experts quickly and efficiently. Organizations can implement Peppy to allow their employees to chat or have a video consultation with specialist healthcare professionals.

34. Twin Health

  • Location: Mountain View, California
  • Founders: Jahangir Mohammed, Maluk Mohamed, Terrence Poon
  • Founded In: 2018
  • Funding: $198.5 Million
  • Investors Include: ICONIQ Growth, Sequoia Capital, Corner Ventures

Twin Health is combining data and information from sensors, machine learning, and medical science in order to reverse chronic diseases and help people live better, more healthy lives.

35. Olive

  • Location: Columbus, Ohio
  • Founders: Bradley Mascho, Sean Lane
  • Founded In: 2012
  • Funding: $856.3 Million
  • Investors Include: Vista Equity Partners, Tiger Global Management

Olive is a healthcare artificial intelligence (AI) company that is creating the “Internet of Healthcare.” Their AI-powered solutions deliver interoperability and connectivity to healthcare administrators and modernize legacy systems and technologies.

36. Oura Ring

  • Location: Oulu, Finland
  • Founders: Kari Kivela, Markku Koskela, Petteri Lahtela
  • Founded In: 2013
  • Funding: $148.3 Million
  • Investors Include: Elysian Park Ventures

The Oura Ring is a sleek, small ring that users can put on while sleeping in order to get information about their sleep habits, sleep times, and sleep quality. Oura is helping millions of people around the world improve their sleep and improve their lives as a result.

37. Cityblock Health

  • Location: Brooklyn, New York
  • Founders: Bay Gross, Iyah Romm, Mat Balez, Toyin Ajayi
  • Founded In: 2017
  • Funding: $891.3 Million
  • Investors Include: SoftBank, Tiger Global Management, 8VC

Cityblock Health works with patients and insurance providers in order to address gaps in current care, split cost savings, and make healthcare a more enjoyable experience for everyone involved. They are using technology to bring health to underserved communities.

38. Honor

  • Location: Concord, California
  • Founders: Cameron Ring, Monica Lo, Sandy Jen, Seth Sternberg
  • Founded In: 2014
  • Funding: $625 Million
  • Investors Include: Baillie Gifford, Perceptive Advisors

Honor is dedicated to changing the aging experience by leading the world’s largest home care network with the most advanced care platform technologies available today. They are revolutionizing how our society takes care of older adults, care professionals, and their families.

Recommended: Check out our full list of the top startups to watch in 2022!


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