4 Top Venture Capital Firms in Wisconsin


Wisconsin has a robust startup ecosystem that several venture capital firms support. In addition, the state has many resources and programs that help startups succeed. The state has a strong culture of entrepreneurship and innovation. This culture is supported by several initiatives, including the Wisconsin Economic Development Corporation's (WEDC) Wisconsin Entrepreneurs' Conference — the largest conference of its kind in the Midwest.

Several VC firms provide startup support, capital, and other resources. These organizations can help startups connect with experienced entrepreneurs who can provide guidance and advice.

We also recommend checking out our full list of the top venture capital firms.

Top Venture Capital Firms in Wisconsin Article.

Best Wisconsin VC Firms

1. Venture Investors

  • Location: Madison, WI
  • Industries: Healthcare
  • Stage: Seed Stage
  • Notable Portfolio Companies: Intralase, Inviragen, Nimblegen

Venture Investors is a VC firm that assists businesses in making crucial decisions and succeeding in the industry. The firm invests in remarkable ideas created by entrepreneurs that will shape the future of the healthcare industry. 

The firm mainly seeks out innovative concepts to generate positive changes in the healthcare sector. They typically invest between $250K and $2.5M.

2. 4490 Ventures

  • Location: Madison, WI
  • Industries: Technology
  • Stage: Seed Stage
  • Notable Portfolio Companies: Abodo, Audience.ai, Avid Ratings

Madison's 4490 Ventures is a renowned VC firm. Entrepreneurs can count on finding investors, founders, and operators at this firm to help them create the next generation of technology companies by bringing funding, company-building know-how, and a wide range of resources. 

They focus on those who desire to change the future by creating innovative ideas. They usually invest between $5 million and $8 million in the initial phase. 

3. HealthX Ventures

  • Location: Madison, WI
  • Industries: Healthcare
  • Stage: Seed Stage
  • Notable Portfolio Companies: Agathos, CancerIQ, CareSignal

Madison-based HealthX Ventures is a VC firm focused on healthcare. They seek to invest in innovative businesses that can improve healthcare safety, efficiency, and affordability. Because they want to provide simple-to-use, cost-effective, and scalable solutions for the healthcare industry, they seek to come up with solutions. Furthermore, the firm provides extensive operational support, deep industry knowledge, and executive-level networking services to its partners. 

4. American Family Ventures

  • Location: Madison, WI
  • Industries: Technology
  • Stage: Seed Stage, Series B
  • Notable Portfolio Companies: Hover, Clearcover, Vesper

American Family Ventures is a venture capital firm that understands all startups' difficulties and hazards and provides them with the capital they need when they need it most. The firm focuses on investing in and educating its collaborating entrepreneurs in order to improve and become more valuable assets. They normally invest up to $5 million.