18 Top Denver Startups to Watch in 2022

Denver Colorado.

There is no question that Denver, Colorado has become a startup powerhouse in recent years. With an influx of both entrepreneurs and investors, the Mile High City is quickly becoming one of the most important tech startup ecosystems in the country. If you are an entrepreneur looking for your next big growth opportunity, or an investor looking to get involved in some of the hottest companies, then you need to be watching Denver.

In this article, we’ll go over some of the top Denver startups to watch in 2022. We’ll provide information on their investors, funding amounts, founders, industry, and more.

Learn how to launch your own company by reading our comprehensive guide on how to start a startup.

Best Startups in Denver to Follow

Every year, new startups pull to the forefront of their industry through exciting innovation, tech, and industry-disrupting business models. We’ve rounded up the most exciting Denver startups of 2022 that startup lovers, investors, and aspiring entrepreneurs should follow.

Disclaimer: With so many exciting startups in Denver launching and growing, we aren’t able to cover them all. Furthermore, the startups that are listed below are not officially ranked and are listed in no particular order.

1. Stack Infrastructure

  • Industry: Information Technology
  • Founders: Brian Cox
  • Founded In: 2019
  • Funding: Debt Financing, $1.4 Billion
  • Investors Include: N/A

Stack Infrastructure creates digital infrastructures that fit the needs of individuals. The structures are fast, scalable, reliable, and built exactly for the needs of the clients. The advanced development team, near-limitless land, and power capacity solve some of the current challenges businesses face today.

2. Guild Education

  • Industry: Education
  • Founders: Brittany Stich, Chris Romer, Rachel Carlson
  • Founded In: 2015
  • Funding: Series F, $643.2 Million
  • Investors Include: Bessemer Venture Partners, Wellington Management

Guild Education is marketed towards businesses that are looking to attract and retain employees by offering continual education classes. The platform allows businesses to offer low-risk and high-reward programs to employees in order to better their careers.

Discover more edtech startups transforming the learning experience.

3. Strive Health

  • Industry: Medical
  • Founders: Chris Riopelle, Will Stokes
  • Founded In: 2018
  • Funding: Series B, $220 Million
  • Investors Include: Town Hall Ventures, Ascension Ventures

Strive Health is helping patients who suffer from chronic kidney disease by offering care delivery models that improve patient health and decrease the cost of care. The company works with both payors and providers in order to put patient care first, improve outcomes, and lower the cost of healthcare for chronic kidney disease and end-stage renal disease.

4. CyberGRX

  • Industry: Cybersecurity
  • Founders: Fred Kneip
  • Founded In: 2015
  • Funding: Series D, $99 Million
  • Investors Include: Scale Venture Partners, Ten Eleven Ventures

CyberGRX is giving companies security against cyber risk and reputation by gathering and providing data intelligence. Companies will be able to protect their third-party digital ecosystem thanks to the data-driven approach CyberGRX is providing.

See our full list of cybersecurity startups to follow.

5. Accept.inc

  • Industry: Real Estate
  • Founders: Adam Pollack, Ian Perrex, Nate Gruendemann, Nick Friedman
  • Founded In: 2016
  • Funding: Debt Financing, $92.1 Million
  • Investors Include: Signal Fire, Rivonia Road Capital

Accept.inc is in the real estate industry and is empowering all homeowners to make all-cash offers with no additional cost to the homeowner. The iLender is able to approve homebuyers who are already approved for a mortgage with cash in order to win their home due to high competition.

 Feeling inspired? Learn how to launch your company with our guide on how to start a startup

6. Last Gameboard

  • Industry: Gaming
  • Founders: Rob Wyatt, Shail Mehta, Tim Schukar
  • Founded In: 2019
  • Funding: Seed, $5 Million
  • Investors Include: TheVentureCity, Conscience VC

Last Gameboard is integrating the in-person and online gaming experience by creating tabletop games that merge digital and analog experiences. Gamers are able to play with anyone, anywhere, and with any game pieces. The tech mimics hand movements in real-life on the surface of a screen.

Explore more of the top gaming startups.

7. Revnt

  • Industry: Education
  • Founders: Alex Vanston, Chris Deardorff
  • Founded In: 2020
  • Funding: Pre-seed, $400k
  • Investors Include: N/A

Revnt is taking educational classes that are offered through video and giving educators the chance to monetize them using a subscriber model. All entrepreneurs and small businesses can use the platform to host a series of educational content and then charge subscribers for access.

8. FlightLink

  • Industry: Aviation
  • Founders: Tom Filippini
  • Founded In: 2019
  • Funding: Seed, $800,000
  • Investors Include: N/A

The lack of personnel in the aviation industry is being addressed by FlightLink, which is creating a private aviation solution. The platform is membership driven and gives like-minded travelers the opportunity to connect, fly affordably, and travel with ease.

9. Spore

  • Industry: Software
  • Founders: Austin Hallock
  • Founded In: 2021
  • Funding: Pre-Seed, $1 Million
  • Investors Include: SignalFire, Goat Capital

Spore is targeted toward content creators and gives them an easy way to create a home for themselves on the internet. The purpose is to give content creators independence from big-name platforms that often take large amounts of fees and give little back to the creators.

Check out our full list of the top software startups.

10. UP

  • Industry: Startup
  • Founders: Hans Schaler, Michael Gallagher, Emily Ahrens, Abe Nadar
  • Founded In: 2021
  • Funding: Pre-seed, $1 Million
  • Investors Include: N/A

UP knows how hard it can be for entrepreneurs and has created a platform that offers simple tools any startup founder can use. The tools help find investors, save money, and even gain more knowledge about startup culture to better the chances of success. Entrepreneurs will be able to pitch to thousands of investors, get discounts on business tools, and gain crucial insights.

11. DispatchHealth

  • Industry: Healthcare
  • Founders: Kevin Riddleberger, Mark Prather
  • Founded In: 2013
  • Funding: Series D, $403.2 Million
  • Investors Include: Questa Capital Management, Tiger Global Management

With DispatchHealth, individuals are able to gain the power of mobile and virtual healthcare all from the comfort of their own homes. The platform caters to a range of ages and patients can get same-day healthcare for a serious injury or illness. Medicare and medicare advantage are both included in the platform.

See more of the top healthcare startups.

12. Havenly

  • Industry: Interior Design
  • Founders: Emily Motayed, Jessie Dixon, Lee Mayer
  • Founded In: 2014
  • Funding: $85.8 Million
  • Investors Include: Suttona Capital, Forward Venture Capital

Havenly takes interior design and adds both personalization and customized care. The platform helps individuals who are looking to design their homes by offering one-on-one design help with hand-picked products that are specifically tailored to the style, space, and budget of the client.

13. Leafwire

  • Industry: Cannabis
  • Founders: Peter Vogel
  • Founded In: 2018
  • Funding: Seed, $1 Million
  • Investors Include: Silverleaf Venture Partners, One East Partners

Leafwire is a cannabis platform that exists to provide resources and opportunities for businesses and employees in the cannabis industry. The Leafwire community is a safe space for business owners to network, find deals, and collaborate with one another. Individuals looking for employment can also find jobs or search through the "greenpages" for better opportunities.

14. Manatee

  • Industry: Healthcare
  • Founders: Damayanti Dipayana, Shawn Kuenzler
  • Founded In: 2018
  • Funding: Seed, $1.7 Million
  • Investors Include: SpringTime Ventures, Grand Ventures

Manatee is attempting to democratize the mental health care system and streamline communication. The platform uses a family app that focuses on family connections to get results within six weeks.

Looking to discover more startups in Colorado? Check out our list of the top Boulder startups to watch.

15. Vantage Data Centers

  • Industry: Data
  • Founders: Jim Trout
  • Founded In: 2010
  • Funding: Private Equity, $7.8 Billion
  • Investors Include: Colony Capital, Silver Lake

Building top-of-the-line data centers, Vantage Data Centers is state-of-the-art and offers hyperscale cloud solutions for large enterprises. The company is able to provide customized data center solutions for any business needs.

16. Crusoe Energy Systems

  • Industry: Energy
  • Founders: Chase Lochmiller, Cully Cavness
  • Founded In: 2018
  • Funding: Series C, $747.5 Million
  • Investors Include: Winklevoss Capital, FootPrint Coalition

Crusoe Energy Systems is creating solutions to reduce the routine flaring of natural gasses for the energy industry. Its mission is to align the future of computation with the future of climate.

17. Ordermark

  • Industry: Food and Beverage
  • Founders: Alex Canter, Paul Allen, Mike Jacobs, Jay Fuhr
  • Founded In: 2017
  • Funding: Series C, $150.9 Million
  • Investors Include: Sand Hill Angels, Republic Capital

Ordermark is taking the complex online ordering platforms that restaurants have to use and consolidating all the information into one dashboard. The platform will help lower costs, inefficiencies, and mistakes by restaurants.

Check out more food and beverage startups to watch.

18. Long Play

  • Industry: Cannabis
  • Founders: N/A
  • Founded In: 2021
  • Funding: $114.7 Million
  • Investors Include: N/A

Long Play is a national cannabis portfolio company looking to help adult-use, medical, and wellness markets with high-quality and high-THC products and hemp consumer packaged goods. The company is led by Willie Nelson's award-winning brands, which enrich experiences, spark connections, and provide opportunities for exploration.

Recommended: Check out our full list of the top startups to watch!

FAQs

Is Denver good for startups?

Yes, Denver is a great place for startups. There are a number of resources and funding opportunities available, and the city has a thriving startup scene. Additionally, Denver is centrally located and has a strong business community.

How many startups are in Denver?

There are hundreds of startups in the city of Denver that have combined to raise a total of over $2 billion in Q2 of 2022 alone. These startups range in industries from cannabis to healthcare.

What big tech companies are in Denver?

The biggest tech companies in Denver are Wordplay, TeleTech, Google, and Arrow Electronics. These companies are headquartered in the city and have a large presence in the tech community.


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