10 Top Buffalo Startups to Watch in 2024

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In recent years, Buffalo, New York, has become somewhat of a startup haven and is now considered by many tech startups as a solid alternative to Silicon Valley. Buffalo startups are able to benefit from the city's impressive offering of incubators and accelerators to secure funding, and the Buffalo startup community is now flourishing more than ever before.

Let's take a look at 10 of the most exciting Buffalo startups to watch in 2024.

Learn how to launch your own company by reading our comprehensive guide on how to start a startup.

Best Startups in Buffalo to Follow

Every year, new startups pull to the forefront of their industry through exciting innovation, tech, and industry-disrupting business models. We’ve rounded up the top Buffalo startups of 2024 that startup lovers, investors, and aspiring entrepreneurs should follow.

Disclaimer: With so many exciting startups launching and growing, we aren’t able to cover them all. Furthermore, the startups that are listed below are not officially ranked and are listed in no particular order.

1. Circuit Clinical

  • Industry: Healthcare Services 
  • Founders: Irfan Khan
  • Founded In: 2015
  • Funding: $59.1 Million 
  • Investors Include: Launch NY, Breakout Ventures 

Circuit Clinical is a startup that has created the world's first patient rating and review platform for clinical trials. Circuit Clinical strives to transform the way that people find and participate in clinical trials and partners with pharmaceutical and biotechnology companies all over the country to help them test and research their products.

2. Verivend

  • Industry: Fintech 
  • Founders: Aaron Santarosa, Jonathan Ebel, Rodney Reisdorf
  • Founded In: 2019
  • Funding: $4.1 Million
  • Investors Include: 43North, Launch NY 

Collecting payment as a business owner is sometimes an unwanted adventure. To reduce friction and risk for accounts payable and accounts receivable transactions, Verivend provides reputation verification, real-time messaging, dispute resolution, and a trusted network of buyers and suppliers.

Discover more top fintech startups.

3. Kangarootime

  • Industry: Childcare 
  • Founders: Scott Wayman
  • Founded In: 2015
  • Funding: $37.5 Million
  • Investors Include: Cultivation Capital, Education Growth Partners 

The childcare industry is one that has yet to fully embrace the digital revolution. Kangarootime, however, is a Buffalo startup that is attempting to change this by offering a comprehensive childcare platform that simplifies billing, parent engagement, reporting, enrollment, and more.

4. Ognomy

  • Industry: Healthcare Services 
  • Founders: Dr. Dan Rifkin, Greg Ross
  • Founded In: 2021 
  • Funding: $2.8 Million
  • Investors Include: Launch NY, Inspire Medical Systems 

It is estimated that 30 million people in the United States suffer from sleep apnea, but only 6 million people have been diagnosed with the condition. Ognomy is a startup that is attempting to help patients who suffer from sleep apnea get diagnosed and receive treatment by offering virtual sleep apnea testing.

5. HELIXintel

  • Industry: Industrial 
  • Founders: Jon DeWald, Michael Mainier, Peter Burakowski
  • Founded In: 2020
  • Funding: $6.7 Million
  • Investors Include: Motivate Venture Capital, Munich Re Ventures

Almost every industry relies on some type of equipment, and if there's one thing that equipment is prone to doing it is breaking down. HELIXintel is a startup that helps companies across all industries maintain their equipment by offering a platform for tracking maintenance issues and tasks and ordering new parts.

Feeling inspired? Learn how to launch your company with our guide on how to start a startup.

6. Peeva

  • Industry: Veterinary 
  • Founders: Michael Hamilton
  • Founded In: 2016
  • Funding: Unknown
  • Investors Include: Unknown

Peeva offers a Universal Pet Microchip Identification System, a Central Microchip Registry, and a Unified Database of Electronic Medical Records for Pets. With these solutions, Peeva strives to make microchip scanning the standard for all vets and shelters.

Explore more top pet startups.

7. Thimble

  • Industry: Retail 
  • Founders: David Brenner, Oscar Pedroso
  • Founded In: 2015
  • Funding: $395,800
  • Investors Include: Google for Startups, ValueStream Ventures 

Thimble is a startup built for those who love to tinker. Operating on a subscription model, Thimble delivers monthly electronics project kits for hobbyists and students. Thimble is also one of Buffalo's most successful crowdfunding stories, managing to raise over $300,000 from crowdfunding.

8. Pointman (Acquired by ServiceTitan)

  • Industry: Home Services 
  • Founders: Stephen Kiernan II, Steve Raines
  • Founded In: 2017
  • Funding: Unknown
  • Investors Include: Unknown 

Pointman is a SaaS company that provides growth-focused solutions to plumbers, HVAC technicians, electricians, and other contractors. By providing these businesses with high-quality tools and coaching, Pointman helps contractors manage and grow their businesses more efficiently and strategically.

9. NexGen Virtual Office

  • Industry: B2B Tech 
  • Founders: Antoinette Forth, Toni Portmann
  • Founded In: 2015
  • Funding: $875,000
  • Investors Include: Launch NY

Even before the COVID-19 pandemic forced businesses to send their employees home, the popularity of remote work was rapidly growing. To improve collaboration between remote employees, NexGen Virtual Office (previously Walkabout Workplace) offers a unique virtual office environment where employees can come together to work.

10. 3AM Innovations

  • Industry: Civic Tech 
  • Founders: Patrick O'Connor, Ryan Litt
  • Founded In: 2015
  • Funding: $11.2 Million
  • Investors Include: BIRD Foundation, URBAN-X

The mission of 3AM Innovations is to help more first responders come home safely. The company offers wearable tracking devices and a mobile command platform called FLORIAN that provides incident commanders with complete on-scene awareness of their personnel and tactics.

Recommended: Check out our full list of the top startups to watch!


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